PROF. SALVATORE VINCENZO GIOFRE'


sgiofre@unime.it

ID scopus: 16309695300

0906766566

Il Prof. Salvatore Vincenzo Giofrè si è laureato cum laude in Chimica e Tecnologia Farmaceutiche presso l’Università di Messina nel 2005. Ha conseguito il titolo di Dottore di Ricerca in “Scienze Farmaceutiche” nel 2009.

Il Prof. Giofrè è Professore Associato per il SSD CHIM/06 (Chimica Organica) presso il Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali dell’Università degli Studi di Messina.

Fa parte del collegio dei docenti del Dottorato in “Scienze Chimiche” presso l’Università di Messina.

Dal 2020 è docente di Chimica Organica del Corso di Laurea Triennale in Biotecnologie presso il Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali dell’Università di Messina.

E’ stato docente di Chimica Organica del Corso di Laurea Triennale in Scienze Farmaceutiche Applicate e Prodotti per la Salute, Chimica Organica Superiore e Metodi Fisici in Chimica Organica del Corso di Laurea Magistrale in Chimica e Tecnologia Farmaceutiche, Laboratorio di Chimica Organica I del Corso di Laurea Triennale in Chimica e Chimica Verde del Corso di Laurea Magistrale in Chimica.

Fa parte dell’Accademia Peloritana dei Pericolanti

E’ membro dell’Editorial Board Atti Della Accademia Peloritana dei Pericolanti – Classe di Scienze Medico-Biologiche.

E’ membro dell’Editorial Board di Letters in Organic Chemistry, ISSN: 1875-6255 Online, ISSN: 1570-1786. Organics, MDPI, ISSN 2673-401X.

E’ Review Editor, Frontiers in Chemistry, ISSN: 2296-2646 Online.

E’ stato Guest Editor Special Issue: New Synthetic Method: Current Opinion in Green and Sustainable Chemistry, Elsevier.

E’ stato Membro del Comitato Organizzatore VI Italian Spanish Symposium on Organic Chemistry. Capo Taormina Hotel, Taormina dal 14-07-2006 al 17-07-2006. Membro del Comitato Organizzatore XXXII Convegno Nazionale della Divisione di Chimica Organica della Società Chimica Italiana. Capo Taormina Hotel, Taormina, Italia dal 26-07-2008 al 30-07-2008. Membro del Comitato Organizzatore XX Symposium “Scientific Days of the Consortium CINMPIS”. Microsoft Teams 7-8 settembre 2021. Membro del Comitato Organizzatore XIX Convegno Nazionale sulle Reazioni Pericicliche e Sintesi di Etero e Carbocicli, Reggio Calabria il 29-30 giugno 2023.

Il Prof. Giofrè è ad oggi autore di 90 pubblicazioni su riviste internazionali citate più di 2400 volte con H index = 30, con un I.F. totale maggiore di 300 e un I.F. medio per pubblicazione di circa 4 (Fonte Scopus e Isiweb Gennaio 2025), 1 brevetto, 2 capitoli di libro e numerose partecipazioni a convegno nazionali ed internazionali. La sua attività scientifica riguarda principalmente le diverse metodologie della sintesi organica, la chimica dei composti eterociclici, le reazioni pericicliche, la chimica degli intermedi reattivi e dei meccanismi di reazione, per applicazioni in ambito farmaceutico e della chimica dei materiali.

PUBBLICAZIONI

  • Sarà, M., Giofrè, S.V., Abate, S., Trapani, M., Verduci, R., D’Angelo, G., Castriciano, M.A., Romeo, A., Neri, G., Monsù Scolaro, L. Absorption and Fluorescence Emission Investigations on Supramolecular Assemblies of Tetrakis-(4-sulfonatophenyl)porphyrin and Graphene Quantum Dots. Molecules, 2024, 29 (9), art. no. 2015. DOI: 10.3390/molecules29092015
  • Chiacchio, M.A., Campisi, A., Iannazzo, D., Giofrè, S.V., Legnani, L. Design of New Schiff Bases and Their Heavy Metal Ion Complexes for Environmental Applications: A Molecular Dynamics and Density Function Theory Study. International Journal of Molecular Sciences, 2024, 25 (8). DOI: 10.3390/ijms25084159
  • Romeo, R., Legnani, L., Chiacchio, M.A., Giofré, S.V., Iannazzo, D. Antiviral Compounds to Address Influenza Pandemics: An Update from 2016-2022. Current Medicinal Chemistry, 2024, 31 (18), 2507-2549. DOI: 10.2174/0929867331666230907093501
  • Iannazzo, D., Celesti, C., Giofrè, S.V., Ettari, R., Bitto, A. Theranostic Applications of 2D Graphene-Based Materials for Solid Tumors Treatment. Nanomaterials, 2023, 13 (16), art. no. 2380. DOI: 10.3390/nano13162380
  • Iannazzo, D., Giofré, S.V. Editorial overview: New synthetic methods: How chemistry change course for a sustainable future. Current Opinion in Green and Sustainable Chemistry, 2023, 41, art. no. 100828. DOI: 10.1016/j.cogsc.2023.100828
  • Smeriglio, A., Iraci, N., Denaro, M., Mandalari, G., Giofrè, S.V., Trombetta, D. Synergistic Combination of Citrus Flavanones as Strong Antioxidant and COX-Inhibitor Agent. Antioxidants, 2023, 12 (4), art. no. 972. DOI: 10.3390/antiox12040972
  • Giofrè, S.V., Celesti, C., Mistretta, G., Tiecco, M. Affinity of deep eutectic solvents with aromatic molecules and aromatic nanostructures in chemical transformations. Current Opinion in Green and Sustainable Chemistry, 2023, 40, art. no. 100779. DOI: 10.1016/j.cogsc.2023.100779
  • Iannazzo, D., Celesti, C., Espro, C., Ferlazzo, A., Giofrè, S.V., Scuderi, M., Scalese, S., Gabriele, B., Mancuso, R., Ziccarelli, I., Visalli, G., Di Pietro, A. Orange-Peel-Derived Nanobiochar for Targeted Cancer Therapy. Pharmaceutics, 2022, 14 (10), art. no. 2249. DOI: 10.3390/pharmaceutics14102249
  • Legnani, L., Giofré, S.V., Iannazzo, D., Celesti, C., Veltri, L., Chiacchio, M.A. Chemoselective Oxidation of Isoxazolidines with Ruthenium Tetroxide: A Successful Intertwining of Combined Theoretical and Experimental Data. Molecules, 2022, 27 (17), art. no. 5390.DOI: 10.3390/molecules27175390
  • Chiacchio, M.A., Iannazzo, D., Giofrè, S.V., Romeo, R., Legnani, L. Ruthenium tetroxide oxidation of N-methyl-isoxazolidine: Computational mechanistic study. Arabian Journal of Chemistry, 2022, 15 (9), art. no. 104063. DOI: 10.1016/j.arabjc.2022.104063
  • Iraci, N., Corsaro, C., Giofrè, S.V., Neri, G., Mezzasalma, A.M., Vacalebre, M., Speciale, A., Saija, A., Cimino, F., Fazio, E. Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs. Biomolecules, 2022, 12 (8), art. no. 1060. DOI: 10.3390/biom12081060
  • Celesti, C., Gervasi, T., Cicero, N., Giofrè, S.V., Espro, C., Piperopoulos, E., Gabriele, B., Mancuso, R., Vecchio, G.L., Iannazzo, D. Titanium Surface Modification for Implantable Medical Devices with Anti-Bacterial Adhesion Properties. Materials, 2022, 15 (9), art. no. 3283. DOI: 10.3390/ma15093283
  • Giofrè, S.V., Tiecco, M., Ferlazzo, A., Romeo, R., Ciancaleoni, G., Germani, R., Iannazzo, D. Base-Free Copper-Catalyzed Azide-Alkyne Click Cycloadditions (CuAAc) in Natural Deep Eutectic Solvents as Green and Catalytic Reaction Media** European Journal of Organic Chemistry, 2021 (34), 4777-4789. DOI: 10.1002/ejoc.202100698
  • Speciale, A., Muscarà, C., Molonia, M.S., Cimino, F., Saija, A., Giofrè, S.V. Silibinin as potential tool against SARS-Cov-2: In silico spike receptor-binding domain and main protease molecular docking analysis, and in vitro endothelial protective effects. Phytotherapy Research, 2021, 35 (8), 4616-4625. DOI: 10.1002/ptr.7107
  • Giofrè, S.V., Napoli, E., Iraci, N., Speciale, A., Cimino, F., Muscarà, C., Molonia, M.S., Ruberto, G., Saija, A. Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in-silico study through molecular docking and dynamics simulations. Computers in Biology and Medicine, 2021, 134, art. no. 104538. DOI: 10.1016/j.compbiomed.2021.104538
  • Scimone, C., Alibrandi, S., Donato, L., Giofrè, S.V., Rao, G., Sidoti, A., D’Angelo, R. Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin. Journal of Clinical Pharmacy and Therapeutics, 2021, 46 (2), 304-309. DOI: 10.1111/jcpt.13315
  • Romeo, R., Giofrè, S.V., Chiacchio, M.A., Veltri, L., Celesti, C., Iannazzo, D. Synthesis and biological evaluation of 2,3,4-triaryl-1,2,4-oxadiazol-5-ones as p38 mapk inhibitors. Molecules, 2021, 26 (6), art. no. 1745. DOI: 10.3390/molecules26061745
  • Giofrè, S.V., Tiecco, M., Celesti, C., Patanè, S., Triolo, C., Gulino, A., Spitaleri, L., Scalese, S., Scuderi, M., Iannazzo, D. Eco-friendly 1,3-dipolar cycloaddition reactions on graphene quantum dots in natural deep eutectic solvent. Nanomaterials, 2020, 10 (12), art. no. 2549, pp. 1-15. DOI: 10.3390/nano10122549
  • Iannazzo, D., Ettari, R., Giofrè, S., Eid, A.H., Bitto, A. Recent advances in nanotherapeutics for multiple myeloma. Cancers, 2020, 12 (11), art. no. 3144, 1-16. DOI: 10.3390/cancers12113144
  • Legnani, L., Iannazzo, D., Pistone, A., Celesti, C., Giofrè, S., Romeo, R., Di Pietro, A., Visalli, G., Fresta, M., Bottino, P., Blanco, I., Chiacchio, M.A. Functionalized polyhedral oligosilsesquioxane (POSS) based composites for bone tissue engineering: Synthesis, computational and biological studies. RSC Advances, 2020, 10 (19), 11325-11334. DOI: 10.1039/d0ra01636e
  • Pistone, A., Iannazzo, D., Celesti, C., Scolaro, C., Giofré, S.V., Romeo, R., Visco, A. Chitosan/PAMAM/Hydroxyapatite engineered drug release hydrogels with tunable rheological properties. Polymers, 2020, 12 (4), art. no. 0754. DOI: 10.3390/polym12040754
  • Giofrè, S.V., Mancuso, R., Araniti, F., Romeo, R., Iannazzo, D., Abenavoli, M.R., Gabriele, B. Microwave-Assisted Synthesis of Sulfurated Heterocycles with Herbicidal Activity: Reaction of 2-Alkynylbenzoic Acids with Lawesson’s Reagent. ChemPlusChem, 2019, 84 (7), 942-950. DOI: 10.1002/cplu.201900316
  • Mancuso, R., Ferlazzo, N., De Luca, G., Amuso, R., Piccionello, A.P., Giofrè, S.V., Navarra, M., Gabriele, B. Synthesis, computational evaluation and pharmacological assessment of acetylsalicylic esters as anti-inflammatory agents. Medicinal Chemistry Research, 2019, 28 (3), 292-299. DOI: 10.1007/s00044-018-02284-3
  • Iannazzo, D., Pistone, A., Celesti, C., Triolo, C., Patané, S., Giofré, S.V., Romeo, R., Ziccarelli, I., Mancuso, R., Gabriele, B., Visalli, G., Facciolà, A., Di Pietro, A. A smart nanovector for cancer targeted drug delivery based on graphene quantum dots. Nanomaterials, 2019, 9 (2), art. no. 282. DOI: 10.3390/nano9020282
  • Chiacchio, M.A., Lanza, G., Chiacchio, U., Giofrè, S.V., Romeo, R., Iannazzo, D., Legnani, L. Oxazole-based compounds as anticancer agents. Current Medicinal Chemistry, 2019, 26 (41), 7337-7371. DOI: 10.2174/0929867326666181203130402
  • Chiacchio, M.A., Iannazzo, D., Romeo, R., Giofrè, S.V., Legnani, L. Pyridine and pyrimidine derivatives as privileged scaffolds in biologically active agents. Current Medicinal Chemistry, 2019, 26 (40), 7166-7195. DOI: 10.2174/0929867325666180904125400
  • Chiacchio, M.A., Legnani, L., Campisi, A., Paola, B., Giuseppe, L., Iannazzo, D., Veltri, L., Giofrè, S., Romeo, R. 1,2,4-Oxadiazole-5-ones as analogues of tamoxifen: Synthesis and biological evaluation. Organic and Biomolecular Chemistry, 2019, 17 (19), 4892-4905. DOI: 10.1039/c9ob00651f
  • Romeo, R., Iannazzo, D., Veltri, L., Gabriele, B., Macchi, B., Frezza, C., Marino-Merlo, F., Giofrè, S.V. Pyrimidine 2,4-Diones in the design of new HIV RT inhibitors. Molecules, 2019, 24 (9), art. no. 1718. DOI: 10.3390/molecules24091718
  • Zoccali, M., Giuffrida, D., Salafia, F., Giofrè, S.V., Mondello, L. Carotenoids and apocarotenoids determination in intact human blood samples by online supercritical fluid extraction-supercritical fluid chromatography-tandem mass spectrometry. Analytica Chimica Acta, 2018, 1032, 40-47. DOI: 10.1016/j.aca.2018.06.022
  • Smeriglio, A., Giofrè, S.V., Galati, E.M., Monforte, M.T., Cicero, N., D’Angelo, V., Grassi, G., Circosta, C. Inhibition of aldose reductase activity by Cannabis sativa chemotypes extracts with high content of cannabidiol or cannabigerol. Fitoterapia, 2018, 127, 101-108. DOI: 10.1016/j.fitote.2018.02.002
  • Cammilleri, G., Vazzana, M., Arizza, V., Giunta, F., Vella, A., Lo Dico, G., Giaccone, V., Giofrè, S.V., Giangrosso, G., Cicero, N., Ferrantelli, V. Mercury in fish products: what’s the best for consumers between bluefin tuna and yellowfin tuna? Natural Product Research, 2018, 32 (4), 457-462. DOI: 10.1080/14786419.2017.1309538
  • Veltri, L., Giofrè, S.V., Devo, P., Romeo, R., Dobbs, A.P., Gabriele, B. A Palladium Iodide-Catalyzed Oxidative Aminocarbonylation-Heterocyclization Approach to Functionalized Benzimidazoimidazoles. Journal of Organic Chemistry, 2018, 83 (3), 1680-1685. DOI: 10.1021/acs.joc.7b03167
  • Romeo, R., Chiacchio, M.A., Campisi, A., Monciino, G., Veltri, L., Iannazzo, D., Broggini, G., Giofrè, S.V. Synthesis and biological evaluation of pyrimidine-oxazolidin-2-arylimino hybrid molecules as antibacterial agents. Molecules, 2018, 23 (7), art. no. 1754. DOI: 10.3390/molecules23071754
  • Giuffrida, D., Zoccali, M., Giofrè, S.V., Dugo, P., Mondello, L. Apocarotenoids determination in Capsicum chinense Jacq. cv. Habanero, by supercritical fluid chromatography-triple-quadrupole/mass spectrometry. Food Chemistry, 2017, 231, 316-323. DOI: 10.1016/j.foodchem.2017.03.145
  • Iannazzo, D., Pistone, A., Ziccarelli, I., Espro, C., Galvagno, S., Giofré, S.V., Romeo, R., Cicero, N., Bua, G.D., Lanza, G., Legnani, L., Chiacchio, M.A. Removal of heavy metal ions from wastewaters using dendrimer-functionalized multi-walled carbon nanotubes. Environmental Science and Pollution Research, 2017, 24 (17), 14735-14747. DOI: 10.1007/s11356-017-9086-2
  • Trombetta, D., Smeriglio, A., Marcoccia, D., Giofrè, S., Toscano, G., Mazzotti, F., Giovanazzi, A., Lorenzetti, S. Analytical evaluation and antioxidant properties of some secondary metabolites in northern Italian mono-and multi-varietal extra virgin olive oils (EVOOs) from early and late harvested olives. International Journal of Molecular Sciences, 2017, 18 (4), art. no. 797, 14 p. DOI: 10.3390/ijms18040797
  • Iannazzo, D., Pistone, A., Salamò, M., Galvagno, S., Romeo, R., Giofré, S.V., Branca, C., Visalli, G., Di Pietro, A. Graphene quantum dots for cancer targeted drug delivery. International Journal of Pharmaceutics, 2017, 518 (1-2), 185-192. DOI: 10.1016/j.ijpharm.2016.12.060
  • Mancuso, R., Pomelli, C.S., Raut, D.S., Marino, N., Giofrè, S.V., Romeo, R., Sartini, S., Chiappe, C., Gabriele, B. Copper-Catalyzed Recyclable Synthesis of (Z)-3-Alkylideneisoindolinones by Cycloisomerization of 2-Alkynylbenzamides in Ionic Liquids. ChemistrySelect, 2017, 2 (3), 894-899. DOI: 10.1002/slct.201601738
  • Romeo, R., Giofrè, S.V., Chiacchio, M.A. Synthesis and biological activity of unnatural enediynes. Current Medicinal Chemistry, 2017, 24 (32), 1-57. DOI: 10.2174/0929867324666170425095719
  • Giofrè, S.V., Cirmi, S., Mancuso, R., Nicolò, F., Lanza, G., Legnani, L., Campisi, A., Chiacchio, M.A., Navarra, M., Gabriele, B., Romeo, R. Synthesis of spiro[isoindole-1,5′-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction. Beilstein Journal of Organic Chemistry, 2016, 12, 2793-2807. DOI: 10.3762/bjoc.12.278
  • Corsaro, C., Cicero, N., Mallamace, D., Vasi, S., Naccari, C., Salvo, A., Giofrè, S.V., Dugo, G. HR-MAS and NMR towards Foodomics. Food Research International, 2016, 89, 1085-1094. DOI: 10.1016/j.foodres.2016.09.033
  • Chiacchio, M.A., Giofrè, S.V., Romeo, R., Romeo, G., Chiacchio, U. Isoxazolidines as biologically active compounds. Current Organic Synthesis, 2016, 13 (5), 726-749. DOI: 10.2174/1570179412666150914195807
  • Legnani, L., Toma, L., Caramella, P., Chiacchio, M.A., Giofrè, S., Delso, I., Tejero, T., Merino, P. Computational Mechanistic Study of Thionation of Carbonyl Compounds with Lawesson’s Reagent. Journal of Organic Chemistry, 2016, 81 (17), 7733-7740. DOI: 10.1021/acs.joc.6b01420
  • Vadalà, R., Mottese, A.F., Bua, G.D., Salvo, A., Mallamace, D., Corsaro, C., Vasi, S., Giofrè, S.V., Alfa, M., Cicero, N., Dugo, G. Statistical analysis of mineral concentration for the geographic identification of garlic samples from sicily (Italy), Tunisia and Spain. Foods, 2016, 5 (1), art. no. 20, 1-11. DOI: 10.3390/foods5010020
  • Chiacchio, U., Broggini, G., Romeo, R., Gazzola, S., Chiacchio, M.A., Giofrè, S.V., Gabriele, B., Mancuso, R., Floresta, G., Zagni, C. Intramolecular oxidative palladium-catalyzed diamination reactions of alkenyl sulfamates: An efficient synthesis of [1,2,5]thiadiazolo-fused piperazinones. RSC Advances, 2016, 6 (62), 57521-57529. DOI: 10.1039/c6ra13141g
  • Giofrè, S.V., Romeo, R., Mancuso, R., Cicero, N., Corriero, N., Chiacchio, U., Romeo, G., Gabriele, B. A new microwave-assisted thionation-heterocyclization process leading to benzo[c]thiophene-1(3H)-thione and 1H-isothiochromene-1-thione derivatives. RSC Advances, 2016, 6 (25), 20777-20780. DOI: 10.1039/c6ra01329e
  • Giofrè, S.V., Romeo, R., Garozzo, A., Cicero, N., Campisi, A., Lanza, G., Chiacchio, M.A. 5-(3-phosphonated 1H-1,2,3-triazol-4-yl)isoxazolidines: Synthesis, DFT studies and biological properties. Arkivoc, 2015, (7), 253-269.DOI: 10.3998/ark.5550190.p009.353
  • Iannazzo, D., Pistone, A., Visco, A., Galtieri, G., Giofrè, S.V., Romeo, R., Romeo, G., Cappello, S., Bonsignore, M., Denaro, R., Galvagno, S. 1,2,3-Triazole/MWCNT conjugates as filler for gelcoat nanocomposites: New active antibiofouling coatings for marine application. Materials Research Express, 2015, 2 (11), art. no. 115001. DOI: 10.1088/2053-1591/2/11/115001
  • Pantò, S., Sciarrone, D., Maimone, M., Ragonese, C., Giofrè, S., Donato, P., Farnetti, S., Mondello, L. Performance evaluation of a versatile multidimensional chromatographic preparative system based on three-dimensional gas chromatography and liquid chromatography-two-dimensional gas chromatography for the collection of volatile constituents. Journal of Chromatography A, 2015, 1417, 96-103. DOI: 10.1016/j.chroma.2015.09.039
  • Cicero, N., Corsaro, C., Salvo, A., Vasi, S., Giofré, S.V., Ferrantelli, V., Di Stefano, V., Mallamace, D., Dugo, G. The metabolic profile of lemon juice by proton HR-MAS NMR: The case of the PGI Interdonato Lemon of Messina. Natural Product Research, 2015, 29 (20), 1894-1902. DOI: 10.1080/14786419.2015.1012166
  • Sorrenti, V., Vanella, L., Acquaviva, R., Cardile, V., Giofrè, S., Di Giacomo, C. Cyanidin induces apoptosis and differentiation in prostate cancer cells. International Journal of Oncology, 2015, 47 (4), 1303-1310. DOI: 10.3892/ijo.2015.3130
  • Araniti, F., Mancuso, R., Lupini, A., Giofrè, S.V., Sunseri, F., Gabriele, B., Abenavoli, M.R. Phytotoxic potential and biological activity of three synthetic coumarin derivatives as new natural-like herbicides. Molecules, 2015, 20 (10), 17883-17902. DOI: 10.3390/molecules201017883
  • Giofrè, S.V., Romeo, R., Chiacchio, U., Romeo, G., Chiacchio, M.A. Phosphonated n,o-nucleosides: Synthesis and biological evaluation. Mini-Reviews in Organic Chemistry, 2015, 12 (3), 249-257. DOI: 10.2174/1570193×1203150429104924
  • Miroddi, M., Navarra, M., Calapai, F., Mancari, F., Giofrè, S.V., Gangemi, S., Calapai, G. Review of clinical pharmacology of Aloe vera L. in the treatment of psoriasis. Phytotherapy Research, 2015, 29 (5), 648-655. DOI: 10.1002/ptr.5316
  • Giofrè, S.V., Romeo, R., Carnovale, C., Mancuso, R., Cirmi, S., Navarra, M., Garozzo, A., Chiacchio, M.A. Synthesis and biological properties of 5-(1H-1,2,3-triazol-4-yl)isoxazolidines: A new class of C-nucleosides. Molecules, 2015, 20 (4), 5260-5275. DOI: 10.3390/molecules20045260
  • Romeo, R., Carnovale, C., Giofrè, S.V., Chiacchio, M.A., Garozzo, A., Amata, E., Romeo, G., Chiacchio, U. C-5′-Triazolyl-2′-oxa-3′-aza-4’a-carbanucleosides: Synthesis and biological evaluation. Beilstein Journal of Organic Chemistry, 2015, 11, 328-334. DOI: 10.3762/bjoc.11.38
  • Macchi, B., Romeo, G., Chiacchio, U., Frezza, C., Giofrè, S.V., Marino-Merlo, F., Mastino, A. Phosphonated nucleoside analogues as antiviral agents. Topics in Medicinal Chemistry, 2015, 15, 53-92. DOI: 10.1007/7355_2013_28
  • Rescifina, A., Zagni, C., Mineo, P.G., Giofrè, S.V., Chiacchio, U., Tommasone, S., Talotta, C., Gaeta, C., Neri, P. DNA recognition with polycyclic-aromatic-hydrocarbon-presenting calixarene conjugates. European Journal of Organic Chemistry, 2014, (34), 7605-7613. DOI: 10.1002/ejoc.201403050
  • Trombetta, D., Giofre, S.V., Tomaino, A., Raciti, R., Saija, A., Cristani, M., Romeo, R., Siracusa, L., Ruberto, G. Selective COX-2 inhibitory properties of dihydrostilbenes from liquorice leaves-in vitro assays and structure/activity relationship study. Natural Product Communications, 2014, 9 (12), 1761-1764. DOI: 10.1177/1934578×1400901226
  • Romeo, R., Carnovale, C., Giofrè, S.V., Monciino, G., Chiacchio, M.A., Sanfilippo, C., Macchi, B. Enantiomerically pure phosphonated carbocyclic 2′-Oxa-3′-azanucleosides: Synthesis and biological evaluation. Molecules, 2014, 19 (9), 14406-14416. DOI: 10.3390/molecules190914406
  • Romeo, R., Giofrè, S.V., Carnovale, C., Chiacchio, M.A., Campisi, A., Mancuso, R., Cirmi, S., Navarra, M. Synthesis and Biological Activity of Triazole-Appended N,O-Nucleosides. European Journal of Organic Chemistry, 2014, (25), 5442-5447. DOI: 10.1002/ejoc.201402106
  • Cimino, S., Favilla, V., Russo, G.I., Galvano, F., Li Volti, G., Barbagallo, I., Giofrè, S.V., D’Orazio, N., Di Rosa, A., Madonia, M., Morgia, G. Oxidative stress and body composition in prostate cancer and benign prostatic hyperplasia patients. Anticancer Research, 2014, 34 (9), 5051-5056.
  • Bisignano, C., Filocamo, A., Ginestra, G., Giofre’, S.V., Navarra, M., Romeo, R., Mandalari, G. 3,4-DHPEA-EA from Olea Europaea L. is effective against standard and clinical isolates of Staphylococcus sp. Annals of Clinical Microbiology and Antimicrobials, 2014, 13 (1), art. no. 24. DOI: 10.1186/1476-0711-13-24
  • Romeo, R., Navarra, M., Giofrè, S.V., Carnovale, C., Cirmi, S., Lanza, G., Chiacchio, M.A. Synthesis and biological activity of new arenediyne-linked isoxazolidines. Bioorganic and Medicinal Chemistry, 2014, 22 (13), 3379-3385. DOI: 10.1016/j.bmc.2014.04.047
  • Mancuso, R., Ziccarelli, I., Armentano, D., Marino, N., Giofrè, S.V., Gabriele, B. Divergent palladium iodide catalyzed multicomponent carbonylative approaches to functionalized isoindolinone and isobenzofuranimine derivatives. Journal of Organic Chemistry, 2014, 79 (8), 3506-3518. DOI: 10.1021/jo500281h
  • Giofrè, S.V., Romeo, R., Chiacchio, M.A. Phosphonated isoxazolidinyl nucleosides, a new class of modified nucleosides. EuroMediterranean Biomedical Journal, 2014, 9 (8), art. no. 7, 45-55. DOI: 10.3269/1970-5492.2014.9.7
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